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Original ArticleEffectiveness of high dose remifentanil in stopping coughing and laryngospasm in non-paralyzed patients for sophisticated bronchoscopic proceduresBasavana Gouda Goudra, Preet Mohinder Singh1, Amit K. Manjunath, Joel W. Reihmer, Andrew R. Haas2, Anthony R. Lanfranco2, Ashish C. Sinha3, Kassem HarrisDepartments of Anesthesia and 2 Medicine, Hospital from the University of Pennsylvania, three Division of Anesthesiology and Perioperative Medicine, Drexel University College of Medicine, Philadelphia, USA, 1 Department of Anesthesia, PGIMER, Chandigarh, IndiaAddress for correspondence: Dr. Basavana Gouda, Perelman College of Medicine, 680 Dulles Building, 3400 Spruce Street, Philadelphia, PA 19104, USA. E-mail: BasavanaGouda. [email protected] Submission: 13-08-2013 Accepted: 18-09-2013 Abstract: BACKGROUND: Anesthesia for bronchoscopy presents one of a kind challenges, as continuous stimulus because of bronchoscope needs to be obtunded working with drugs using a minimal post-procedure residual impact. Remifentanil for maintenance is an perfect option, but optimal doses are however to become determined. Components AND Solutions: Bronchoscopic procedures have been prospectively evaluated for four months studying the frequency of complications and anesthesia strategies. Anesthesia was maintained on remifentanil/propofol infusion avoiding neuromuscular blockers.1500974-00-4 Data Sheet Laryngeal mask airway was applied for the controlled ventilation (with high oxygen concentration) that also served as a conduit for bronchoscope insertions.PMID:24456950 Anesthesiologists have been blinded for the study (avoiding efficiency bias) as well as the Pulmonologist was blinded to the anesthesia approach (to document unbiased procedural satisfaction scores). Procedures have been divided into 2 groups according to the dose of remifentanil utilised for upkeep: Group-H (higher dose -0.26 to 0.five g/kg/min and Group-NH (non-high dose 0.25 g/kg/min). Benefits: Observed 75 procedures have been divided into Group-H (42) and Group-NH (33). Number of statistical distinction was found in demography, procedural profi.